Resistance to intravenous immunoglobulin (IVIG) in Kawasaki disease: no influence of different IVIG lot utilisation.
نویسندگان
چکیده
منابع مشابه
Predictors of Intravenous Immunoglobulin (IVIG) Resistance in Children with Kawasaki Disease in Calabria Region, Italy
Background Kawasaki disease (KD) is the second most common childhood vasculitis and one of the main causes of acquired heart disease in children. Recent work focuses on the early diagnostic importance of those risk factors that indicate resistance to intravenous immunoglobulin (IVIG) treatment. The objectives of this study were to identify clinical, laboratory and/or instrumental factors that c...
متن کاملUse of Corticosteroid in Children with Unresponsiveness to Intravenous Immunoglobulin in Kawasaki Disease
Background Kawasaki Disease (KD) is a vasculitis with multi-organ involvementof unknown etiology; it is the most common cause of pediatric-heart diseases in developed countries. Treatment with Intravenous Immunoglobulin (IVIG) prevents coronary artery lesions; although there are some IVIG-resistant cases, combination therapy with corticosteroids and IVIG is one of the recommendations for treatm...
متن کاملUses of intravenous immunoglobulin
Adjuvant high dose IVIgs are being used increasingly in a range of immune-mediated and auto-immune diseases. Although numerous immunomodulatory mechanisms have been suggested, the exact mechanisms of action are poorly understood. The efficacy of IVIg in certain diseases has been proven in clinical trials, in so far as IVIg is approved as the therapy of choice for Kawasaki syndrome and idiopathi...
متن کاملFactors Predicting Resistance to Intravenous Immunoglobulin and Coronary Complications in Kawasaki Disease: IVIG Resistance in Kawasaki Disease
https://e-kcj.org Downie et al.1) defined intravenous immunoglobulin (IVIG) resistance in patients with Kawasaki disease (KD) as any patient who receives a second dose of IVIG and had a fever (body temperature [BT] >38.0°C) since finishing the first IVIG dose (2 g/kg). In addition, patients who do not respond to IVIG (BT ≥37.5°C more than 24 hours after the end of IVIG infusion) seem to develop...
متن کاملComparison of early and late intravenous gamma globulin treatment of Kawasaki disease on fever and cardiovascular complications
Background: Cardiac involvement was the major leading cause of death in patients with Kawasaki and IVIG administration reduces cardiac complications. The objective of this study was to determine the frequency of cardiovascular complications and duration of fever with regard to the time of intravenous immunoglobulin (IVIG) administration of patients with Kawasaki disease. Methods: This follow...
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ورودعنوان ژورنال:
- Clinical and experimental rheumatology
دوره 30 1 Suppl 70 شماره
صفحات -
تاریخ انتشار 2012